What is NDC 14222-2120?

14222-2120 is the product NDC for UNBLEMISH Dual Intensive Acne Treatment, Benzoyl peroxide .025 g/mL lotion, listed with the FDA by Rodan & Fields. It has 2 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

UNBLEMISH Dual Intensive Acne Treatment (Benzoyl peroxide).

Rodan & Fields, NDC labeler code 14222. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for UNBLEMISH Dual Intensive Acne Treatment?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

UNBLEMISH Dual Intensive Acne Treatment NDC 14222-2120

NDC codes

FDA NDC Directory

Product NDC (as listed)14222-2120Labeler and product segments. Claims need a package NDC.

Product NDC at billing width14222-2120Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
14222-2120-1	1422221200114222212001	1 BOTTLE, PUMP in 1 CARTON (14222-2120-1) / 45 mL in 1 BOTTLE, PUMPMarketed from Feb 13, 2019
14222-2120-2	1422221200214222212002	1 BOTTLE, PUMP in 1 CARTON (14222-2120-2) / 8 mL in 1 BOTTLE, PUMPMarketed from Mar 1, 2026

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): UNBLEMISH Dual Intensive Acne Treatment
Generic name (nonproprietary): benzoyl peroxide
Active ingredients: Benzoyl peroxide — .025 g/mL
Dosage form: Lotion
Route: Topical
Labeler: Rodan & FieldsNDC labeler code 14222
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 006
Marketing start: Feb 13, 2019
Listing expires: Dec 31, 2027
Identifiers: Product ID 14222-2120_d9302027-e455-4a25-8c7f-d2d960e5b967SPL ID d9302027-e455-4a25-8c7f-d2d960e5b967SPL set ID 27ea743c-e080-487d-adc5-e31176f5b9fcRxCUI 200009UNII W9WZN9A0GMUPC 0884164014482

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N414222212001 followed by a unit qualifier and the quantity

Package 14222-2120-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 30, 2026.

Indications (excerpt from the label)

Uses for the treatment of acne helps keep skin clear of new acne blemishes, acne pimples, blackheads + whiteheads

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 14222-2120

What is NDC 14222-2120?: 14222-2120 is the product NDC for UNBLEMISH Dual Intensive Acne Treatment, Benzoyl peroxide .025 g/mL lotion, listed with the FDA by Rodan & Fields. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: UNBLEMISH Dual Intensive Acne Treatment (Benzoyl peroxide).
What is the active ingredient?: Benzoyl peroxide.
Who is the labeler?: Rodan & Fields, NDC labeler code 14222. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for UNBLEMISH Dual Intensive Acne Treatment?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other NDCs under M 006

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 006
Product	Strength	Form · route	Labeler	Product NDC
Dr. Dennis Gross Alpha Beta On the Spot Eliminatorsalicylic acid	Salicylic acid 20 mg/mL	GelTopical	Topiderm, Inc	51326-057
The INKEY List Salicylic Acid Cleansersalicylic acid	Salicylic acid 20 mg/mL	GelTopical	Brand Evangelists for Beauty Ltd	81136-019
Anubis Barcelonapeg-40 hydrogenated castor oil, propylene glycol, allantoin	Propylparaben .0000001 g/5mL + 26 more ingredients	ConcentrateTopical	ANUBIS COSMETICS SL	83021-617
CAVOREAL Plus Salicylic Acid Anti Acne with BHA HAsalicylic acid	Salicylic acid 1 g/15g	CreamTransdermal	Guangzhou Meijiao Medical Biotechnology Co., Ltd.	87036-033
Perricone MD Acne Relief Gentle Exfoliating Toner Salicylic Acid Acne Treatmentsalicylic acid	Salicylic acid 2 g/100mL	LiquidTopical	THG Beauty USA LLC	84448-602
Sylvirene Milia Removersalicylic acid 1% milia remover	Salicylic acid 1 g/100mL	LiquidTopical	Jiangxi Yudexi Pharmaceutical Co., LTD	85248-071
Proactiv Emergency Blemish Reliefbenzoyl peroxide	Benzoyl peroxide 5 g/100g	CreamTopical	Alchemee, LLC	11410-012
Proactiv Clean Mineral Acne Cleansersulfur	Sulfur 3 g/100mL	CreamTopical	Alchemee, LLC	11410-457
BP Washbenzoyl peroxide	Benzoyl peroxide 25 mg/g	EmulsionTopical	CINTEX SERVICES, LLC	24470-911
Differin Max Strength Acne Foaming BPO Cleanserbenzoyl peroxide	Benzoyl peroxide 10 g/100mL	SolutionTopical	Galderma Laboratories, L.P.	0299-4137
Perricone MD Acne Relief Gentle and Soothing Cleansersalicylic acid	Salicylic acid 2 g/100mL	GelTopical	THG Beauty USA LLC	84448-539
Gly-Sal 5-2 Padssalicylic acid	Salicylic acid .02 g/1	ClothTopical	Topiderm, Inc.	51326-038
UNBLEMISH Refining Acne Washsalicylic acid	Salicylic acid .005 g/mL	CreamTopical	Rodan & Fields	14222-2111
Gly-Sal 10-2 Padssalicylic acid	Salicylic acid .02 g/1	ClothTopical	Topiderm, Inc.	51326-039
Clinicians Complexsulfur	Sulfur 100 mg/g	LotionTopical	SkinSx.com, Inc.	72622-001
Blemish Blitz Emergency Acne Serumsalicylic acid	Salicylic acid .01 g/mL	LiquidTopical	Guangdong Joyan Biological Technology Co.,Ltd	85779-003
CAVOREAL Plus Salicylic Acid Anti Acne with BHA HAsalicylic acid	Salicylic acid 1 g/15mL	CreamTransdermal	Guangzhou Meijiao Medical Biotechnology Co., Ltd.	87036-032
Perricone MD Acne Relief Calming Treatment and Hydrator Salicylic Acid Acne Treatmentsalicylic acid	Salicylic acid .5 g/100mL	CreamTopical	THG Beauty USA LLC	84448-540
Oxy Sensitive Skin Acne Cleansing Padssalicylic acid 0.5%	Salicylic acid 5 mg/1	ClothTopical	The Mentholatum Company	10742-1007
Oxy Total Care Clarifying Moisturizerbenzoyl peroxide	Benzoyl peroxide 25 mg/mL	LotionTopical	The Mentholatum Company	10742-1314

Showing 20 of 39.

UNBLEMISH Dual Intensive Acne Treatment (Benzoyl peroxide) NDC 14222-2120