NDC codes

FDA NDC Directory
Product NDC (as listed)0480-2157Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00480-2157Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0480-2157-57004802157571 BOTTLE, SPRAY in 1 CARTON (0480-2157-57) / 120 SPRAY, METERED in 1 BOTTLE, SPRAYMarketed from Sep 8, 2025

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Azelastine Hydrochloride and Fluticasone Propionate
Generic name (nonproprietary)
azelastine hydrochloride and fluticasone propionate
Active ingredients
Azelastine hydrochloride — 137 ug/1Fluticasone propionate — 50 ug/1
Dosage form
Spray, Metered
Route
Nasal
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 208436
Marketing start
Listing expires
Other FDA classes
Corticosteroid Hormone Receptor Agonists (Mechanism)Histamine H1 Receptor Antagonists (Mechanism)
Identifiers
Product ID 0480-2157_edea3e4b-7afc-4566-864d-acdf480a92afSPL ID edea3e4b-7afc-4566-864d-acdf480a92afSPL set ID 0d45e7a4-900f-44ef-bb18-a1fbff75a3c6RxCUI 1797847UNII 0L591QR10I, O2GMZ0LF5W
Pharmacologic class
Corticosteroid; Histamine-1 Receptor Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Nasal products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400480215757 followed by a unit qualifier and the quantity

Package 00480-2157-57. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Azelastine hydrochloride and fluticasone propionate nasal spray is indicated for the relief of symptoms of seasonal allergic rhinitis in adult and pediatric patients 6 years of age and older. Azelastine hydrochloride and fluticasone propionate nasal spray contains an H 1 -receptor antagonist and a corticosteroid, and is indicated for the relief of symptoms of seasonal allergic rhinitis in adult and pediatric patients 6 years of age and older. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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