NDC codes

FDA NDC Directory
Product NDC (as listed)0404-9857Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00404-9857Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0404-9857-01004049857011 AMPULE in 1 BAG (0404-9857-01) / 1 mL in 1 AMPULEMarketed from Jan 10, 2022

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Epinephrine
Generic name (nonproprietary)
epinephrine
Active ingredients
Epinephrine — 1 mg/mL
Dosage form
Injection, Solution, Concentrate
Route
Intravenous
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 205029
Marketing start
Listing expires
Other FDA classes
Adrenergic alpha-Agonists (Mechanism)Adrenergic beta-Agonists (Mechanism)Catecholamines (Chemical structure)
Identifiers
Product ID 0404-9857_f9cff631-655e-45b8-b870-e7504142977dSPL ID f9cff631-655e-45b8-b870-e7504142977dSPL set ID af10f2bb-b0ad-45a6-b525-e715613350afRxCUI 1660014UNII YKH834O4BH
Pharmacologic class
Catecholamine; alpha-Adrenergic Agonist; beta-Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeMed-Code curated

J0171 — Injection, adrenalin, epinephrine, 0.1 mg

Billing unit: 0.1 mg. Units on the claim = dose given ÷ 0.1 mg.

Applies when epinephrine is administered in a clinical setting. Auto-injectors dispensed to patients are billed by NDC through a pharmacy benefit.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400404985701 followed by a unit qualifier and the quantity

Package 00404-9857-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

1.1 Hypotension associated with Septic Shock Epinephrine Injection USP, 1 mg/mL is indicated to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock. 1.2 Anaphylaxis Emergency treatment of allergic reactions (Type I), including anaphylaxis, which may result from allergic reactions to insect stings, biting insects, foods, drugs, sera, diagnostic testing substances and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis. The signs and symptoms associated with anaphylaxis include flushing, apprehension, syncope, tachycardia, thready or unobtainable pulse associated with hypotension, convulsions, vomiting, diarrhea a…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 205029

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 205029
ProductStrengthForm · routeLabelerProduct NDC
EpinephrineEpinephrine 1 mg/mLInjection, Solution, ConcentrateIntramuscular, Intraocular, Intravenous, SubcutaneousA-S Medication Solutions50090-3039
EpinephrineEpinephrine 1 mg/mLInjection, Solution, ConcentrateIntramuscular, Intraocular, Intravenous, SubcutaneousProPharma Distribution84549-103
EpinephrineEpinephrine 1 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousMedical Purchasing Solutions, LLC.71872-7360
EpinephrineEpinephrine 1 mg/mLInjection, Solution, ConcentrateIntramuscular, Intraocular, Intravenous, SubcutaneousBPI Labs, LLC54288-103
EpinephrineEpinephrine 1 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousBPI Labs, LLC54288-120
EpinephrineEpinephrine 1 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousHF Acquisition Co LLC, DBA HealthFirst51662-1706
EpinephrineEpinephrine 1 mg/mLInjectionIntravenousBPI Labs, LLC54288-117
EpinephrineEpinephrine 1 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousBPI Labs, LLC54288-119
EpinephrineEpinephrine 1 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousREMEDYREPACK INC.70518-4156
EpinephrineEpinephrine 30 mg/30mLInjectionIntramuscular, Intravenous, SubcutaneousBPI Labs, LLC54288-152
EpinephrineEpinephrine 1 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousBPI Labs, LLC54288-600
EpinephrineEpinephrine 1 mg/mLInjection, Solution, ConcentrateIntravenousMedical Purchasing Solutions, LLC71872-7117

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