NDC codes

FDA NDC Directory
Product NDC (as listed)0404-9825Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00404-9825Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0404-9825-10004049825101 VIAL, SINGLE-DOSE in 1 BAG (0404-9825-10) / 10 mL in 1 VIAL, SINGLE-DOSEMarketed from Jan 9, 2022

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Brevibloc
Generic name (nonproprietary)
esmolol hydrochloride
Active ingredients
Esmolol hydrochloride — 10 mg/mL
Dosage form
Injection
Route
Intravenous
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 019386
Marketing start
Listing expires
Other FDA classes
Adrenergic beta-Antagonists (Mechanism)
Identifiers
Product ID 0404-9825_e898a56b-15fa-4ef7-be89-59d27637afe1SPL ID e898a56b-15fa-4ef7-be89-59d27637afe1SPL set ID 38a8b23a-fca8-45f4-a09a-9c8b21f522cdRxCUI 1736546, 1736547UNII V05260LC8D
Pharmacologic class
beta-Adrenergic Blocker

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400404982510 followed by a unit qualifier and the quantity

Package 00404-9825-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

1.1 Supraventricular Tachycardia or Noncompensatory Sinus Tachycardia BREVIBLOC (Esmolol Hydrochloride) injection is indicated for the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. BREVIBLOC injection is also indicated in noncompensatory sinus tachycardia where, in the physician’s judgment, the rapid heart rate requires specific intervention. BREVIBLOC injection is intended for short-term use. 1.2 Intraoperative and Postoperative Tachycardia and/or Hypertension BREVIBLOC (Esmolol Hydrochloride) injecti…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 019386

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 019386
ProductStrengthForm · routeLabelerProduct NDC
Esmolol HydrochlorideEsmolol hydrochloride 10 mg/mLInjectionIntravenousHF Acquisition Co LLC, DBA HealthFirst51662-1427
Esmolol HydrochlorideEsmolol hydrochloride 10 mg/mLInjectionIntravenousMedical Purchasing Solutions, LLC71872-7136
Breviblocesmolol hydrochlorideEsmolol hydrochloride 20 mg/mLInjectionIntravenousBaxter Healthcare Company10019-666
Breviblocesmolol hydrochlorideEsmolol hydrochloride 20 mg/mLInjectionIntravenousBaxter Healthcare Company10019-668
Breviblocesmolol hydrochlorideEsmolol hydrochloride 10 mg/mLInjectionIntravenousBaxter Healthcare Company10019-670
Breviblocesmolol hydrochlorideEsmolol hydrochloride 10 mg/mLInjectionIntravenousBaxter Healthcare Company10019-672
Breviblocesmolol hydrochlorideEsmolol hydrochloride 10 mg/mLInjectionIntravenousBaxter Healthcare Company10019-055
Breviblocesmolol hydrochlorideEsmolol hydrochloride 20 mg/mLInjectionIntravenousBaxter Healthcare Company10019-075
Breviblocesmolol hydrochlorideEsmolol hydrochloride 10 mg/mLInjectionIntravenousBaxter Healthcare Company10019-115
Esmolol HydrochlorideEsmolol hydrochloride 10 mg/mLInjectionIntravenousBaxter Healthcare Corporation10019-120

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