Alka-Seltzer Heartburn Relief Lemon Lime NDC 0280-0083

NDC codes

FDA NDC Directory

Product NDC (as listed)0280-0083Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00280-0083Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
0280-0083-01	00280008301	18 PACKET in 1 CARTON (0280-0083-01) / 2 TABLET, EFFERVESCENT in 1 PACKETMarketed from Feb 16, 2022
0280-0083-02	00280008302	12 PACKET in 1 CARTON (0280-0083-02) / 2 TABLET, EFFERVESCENT in 1 PACKETMarketed from Apr 1, 2024
0280-0083-03	00280008303	36 PACKET in 1 CARTON (0280-0083-03) / 2 TABLET, EFFERVESCENT in 1 PACKETMarketed from Apr 1, 2024

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Alka-Seltzer Heartburn Relief Lemon Lime
Generic name (nonproprietary): anhydrous citric acid, sodium bicarbonate (heat-treated)
Active ingredients: Sodium bicarbonate — 1650 mg/1Citric acid monohydrate — 1000 mg/1
Dosage form: Tablet, Effervescent
Route: Oral
Labeler: Bayer Healthcare LLC
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 001
Marketing start: Feb 16, 2022
Listing expires: Dec 31, 2026
Other FDA classes: Acidifying Activity (Mechanism)Calcium Chelating Activity (Mechanism)Decreased Coagulation Factor Activity (Physiologic effect)Increased Large Intestinal Motility (Physiologic effect)Inhibition Large Intestine Fluid/Electrolyte Absorption (Physiologic effect)Osmotic Activity (Mechanism)
Identifiers: Product ID 0280-0083_31b97b49-1db4-5da9-e063-6394a90a04c3SPL ID 31b97b49-1db4-5da9-e063-6394a90a04c3SPL set ID cc21af24-9a5b-6831-e053-2a95a90a0af4RxCUI 2599360UNII 8MDF5V39QO, 2968PHW8QPUPC 0016500567301
Pharmacologic class: Anti-coagulant; Calculi Dissolution Agent; Osmotic Laxative

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400280008301 followed by a unit qualifier and the quantity

Package 00280-0083-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Apr 1, 2025.

Indications (excerpt from the label)

Uses for the relief of heartburn acid indigestion sour stomach upset stomach associated with these symptoms

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under M 001

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 001
Product	Strength	Form · route	Labeler	Product NDC
Sodium Bicarbonate	Sodium bicarbonate 1000 mg/g	PowderOral	Pharma Nobis, LLC	82645-904
Regular Strength Antacid And Antigasaluminum hydroxide, magnesium hydroxide, dimethicone	Aluminum hydroxide 200 mg/5mL + 2 more ingredients	SuspensionOral	STRATEGIC SOURCING SERVICES LLC	70677-1063
Antacidaluminum hydroxide, magnesium hydroxide, simethicone	Aluminum hydroxide 400 mg/10mL + 2 more ingredients	LiquidOral	Rugby Laboratories	0536-1293
Calcium Carbonate	Calcium carbonate 420 mg/1	Tablet, ChewableOral	Allegiant Health	69168-036
Antacidaluminum hydroxide, magnesium hydroxide, simethicone	Aluminum hydroxide 400 mg/10mL + 2 more ingredients	LiquidOral	Guardian Drug Company	53041-509
Bismuth Subsalicylate	Bismuth subsalicylate 262 mg/1	Tablet, Film coatedOral	CVS Pharmacy, Inc.	69842-346
Unishield Antacidcalcium carbonate	Calcium carbonate 420 mg/1	Tablet, ChewableOral	Unishield	49314-1013
up and up extra strength smooth dissolving antacid Assorted Fruitcalcium carbonate	Calcium carbonate 750 mg/1	Tablet, ChewableOral	Target corporation	11673-715
Good Neighbor Pharmacy Antacid Regular Strengthcalcium carbonate	Calcium carbonate 500 mg/1	Tablet, ChewableOral	AmerisourceBergen Drug Corporation	24385-485
Sanar Baking Soda 8oz 100% puresodium bicarbonate	Sodium bicarbonate 616 mg/g	PowderOral	Evi Labs	84178-104
D-D Sudium Bicarbonate U.S.P. Bicarbonato De Soda Purosodium bicarbonate	Sodium bicarbonate 315 mg/g	PowderOral	Evi Labs	84178-105
Regular Strength Antacid Assorted Fruit Regular strength Antacidcalcium carbonate	Calcium carbonate 500 mg/1	Tablet, ChewableOral	Hyvee Inc	42507-350
Antacid And Antigascalcium carbonate, magnesium hydroxide, simethicone	Calcium carbonate 800 mg/10mL + 2 more ingredients	LiquidOral	Geri-Care Pharmaceuticals, Corp	57896-655
Premier Value Extra Strength Original Flavoraluminum hydroxide and magnesium carbonate	Aluminum hydroxide 160 mg/1; Magnesium carbonate 105 mg/1	Tablet, ChewableOral	PHARMACY VALUE ALLIANCE, LLC	68016-105
Genexa Antacid Maximum Strengthcalcium carbonate	Calcium carbonate 1000 mg/1	Tablet, ChewableOral	Genexa Inc.	69676-0072
ADRIAN BICARBONATO SODIUM BICARBONATE USP-4 oz, 8 oz and 16 ozsodium bicarbonate	Sodium bicarbonate 315 mg/g	PowderOral	Evi Labs	84178-106
meijer extra strength Wintergreen Flavorcalcium carbonate	Calcium carbonate 750 mg/1	Tablet, ChewableOral	MEIJER DISTRIBUTION INC	41250-669
Magnesium Oxide	Magnesium oxide 400 mg/1	TabletOral	Method Pharmaceuticals, LLC	58657-120
Humco Sodium Bicarbonatesodium bicarbonate	Sodium bicarbonate 1000 mg/g	PowderOral	Humco Holding Group, Inc.	0395-2685
Dr Sana Alivio Digestivo Naranja UPSET STOMACHeffervescent antacid	Bicarbonate ion 2485 mg/5000mg	Granule, EffervescentOral	EVI LABS	84178-112

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