NDC codes

FDA NDC Directory
Product NDC (as listed)0259-4150Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00259-4150Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0259-4150-01002594150011 VIAL, SINGLE-USE in 1 CARTON (0259-4150-01) / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL, SINGLE-USEMarketed from Sep 1, 2010

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Xeomin
Generic name (nonproprietary)
incobotulinumtoxina
Active ingredients
Botulinum toxin type a — 50 [USP'U]/1
Dosage form
Injection, Powder, Lyophilized, For solution
Route
Intramuscular
Product type
Prescription drug
Marketing category
BLA — Biologics License ApplicationApplication BLA 125360
Marketing start
Listing expires
Other FDA classes
Acetylcholine Release Inhibitors (Mechanism)Neuromuscular Blockade (Physiologic effect)
Identifiers
Product ID 0259-4150_75c52aa4-0780-4e18-bac3-ba1440a74deeSPL ID 75c52aa4-0780-4e18-bac3-ba1440a74deeSPL set ID ccdc3aae-6e2d-4cd0-a51c-8375bfee9458RxCUI 1000107, 1009456, 1009459, 1732157, 1732161, 1732165UNII E211KPY694UPC 0302594150018, 0302594110012, 0302591605016, 0302591620019, 0302591610010
Pharmacologic class
Acetylcholine Release Inhibitor; Neuromuscular Blocker

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400259415001 followed by a unit qualifier and the quantity

Package 00259-4150-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

XEOMIN is an acetylcholine release inhibitor and neuromuscular blocking agent indicated for the treatment or improvement of: Chronic sialorrhea in patients 2 years of age and older ( 1.1 ) Upper limb spasticity in patients 2 years of age and older ( 1.2 ) Cervical dystonia in adults ( 1.3 ) Blepharospasm in adults ( 1.4 ) the appearance of upper facial lines in adults: moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity ( 1.5 ) moderate to severe horizontal forehead lines associated with frontalis muscle activity ( 1.5 ) moderate to severe lateral canthal lines associated with orbicularis oculi muscle activity ( 1.5 ) 1.1 Chronic Sialorrhea XEOMIN is…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under BLA 125360

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under BLA 125360
ProductStrengthForm · routeLabelerProduct NDC
XeominincobotulinumtoxinaBotulinum toxin type a 100 [USP'U]/1Injection, Powder, Lyophilized, For solutionIntramuscularMerz North America, Inc.46783-160
XeominincobotulinumtoxinaBotulinum toxin type a 50 [USP'U]/1Injection, Powder, Lyophilized, For solutionIntramuscularMerz North America, Inc.46783-161
XeominincobotulinumtoxinaBotulinum toxin type a 50 [USP'U]/1Injection, Powder, Lyophilized, For solutionIntramuscularMerz North America, Inc.46783-165
XeominincobotulinumtoxinaBotulinum toxin type a 50 [USP'U]/1Injection, Powder, Lyophilized, For solutionIntramuscularMerz Pharmaceuticals, LLC0259-1605
XeominincobotulinumtoxinaBotulinum toxin type a 100 [USP'U]/1Injection, Powder, Lyophilized, For solutionIntramuscularMerz Pharmaceuticals, LLC0259-1610
XeominincobotulinumtoxinaBotulinum toxin type a 200 [USP'U]/1Injection, Powder, Lyophilized, For solutionIntramuscularMerz Pharmaceuticals, LLC0259-1620
XeominincobotulinumtoxinaBotulinum toxin type a 100 [USP'U]/1Injection, Powder, Lyophilized, For solutionIntramuscularMerz Pharmaceuticals, LLC0259-4110

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