Clobetasol Propionate NDC 0168-0269

NDC codes

FDA NDC Directory

Product NDC (as listed)0168-0269Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00168-0269Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
0168-0269-50	00168026950	50 mL in 1 BOTTLE, PLASTIC (0168-0269-50)Marketed from Feb 8, 1999

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Clobetasol Propionate
Generic name (nonproprietary): clobetasol propionate
Active ingredients: Clobetasol propionate — .5 mg/mL
Dosage form: Solution
Route: Topical
Labeler: E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 075391
Marketing start: Feb 8, 1999
Listing expires: Dec 31, 2027
Other FDA classes: Corticosteroid Hormone Receptor Agonists (Mechanism)
Identifiers: Product ID 0168-0269_3ae739b7-7eaa-4dbd-a696-a3a0e3998f38SPL ID 3ae739b7-7eaa-4dbd-a696-a3a0e3998f38SPL set ID 736325f3-a369-4d70-b608-3d6ba37b6a6bRxCUI 861487UNII 779619577M
Pharmacologic class: Corticosteroid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400168026950 followed by a unit qualifier and the quantity

Package 00168-0269-50. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 28, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE: Clobetasol propionate topical solution USP, 0.05% is indicated for short-term topical treatment of inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp. Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 mL/week because of the potential for the drug to suppress the HPA axis. This product is not recommended for use in pediatric patients under 12 years of age.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)