NDC codes

FDA NDC Directory
Product NDC (as listed)0078-0846Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00078-0846Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0078-0846-19000780846191 INJECTION, SUSPENSION in 1 BAG (0078-0846-19)Marketed from Aug 30, 2017

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Kymriah
Generic name (nonproprietary)
tisagenlecleucel
Active ingredients
Tisagenlecleucel — 2000000 1/1
Dosage form
Injection, Suspension
Route
Intravenous
Labeler
Novartis Pharmaceuticals CorporationNDC labeler code 0078
Product type
Cellular therapy
Marketing category
BLA — Biologics License ApplicationApplication BLA 125646
Marketing start
Listing expires
Other FDA classes
CD19 Receptor Interactions (Mechanism)CD19-specific Chimeric Antigen Receptor (Chemical structure)Increased T Lymphocyte Activation (Physiologic effect)Genetically-modified (EXT)
Identifiers
Product ID 0078-0846_381f1ba3-f115-424f-9890-75eb06ab6666SPL ID 381f1ba3-f115-424f-9890-75eb06ab6666SPL set ID aad3ba54-dfd3-4cb3-9e2b-c5ef89559189RxCUI 1986442, 1986447, 2044973, 2044975UNII Q6C9WHR03O
Pharmacologic class
CD19-directed Chimeric Antigen Receptor; Genetically-modified Autologous T Cells

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N400078084619 followed by a unit qualifier and the quantity

Package 00078-0846-19. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

KYMRIAH is a CD19-directed genetically modified autologous T cell immunotherapy indicated for the treatment of: Patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse. ( 1.1 ) Adult patients with relapsed or refractory (r/r) large B-cell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, high grade B-cell lymphoma and DLBCL arising from follicular lymphoma. Limitations of Use : KYMRIAH is not indicated for treatment of patients with primary central nervous system lymphoma. ( 1.2 ) Adult patients with relapsed or refractory follicular ly…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 0078-0846

What is NDC 0078-0846?
0078-0846 is the product NDC for Kymriah (tisagenlecleucel), Tisagenlecleucel 2000000 1/1 injection, suspension, listed with the FDA by Novartis Pharmaceuticals Corporation. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Kymriah (Tisagenlecleucel).
What is the active ingredient?
Tisagenlecleucel.
Who is the labeler?
Novartis Pharmaceuticals Corporation, NDC labeler code 0078. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Kymriah?
1 other product NDC are listed under this name. See all Kymriah NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Kymriah NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
KymriahtisagenlecleucelTisagenlecleucel 60000000 1/1Injection, SuspensionIntravenousNovartis Pharmaceuticals Corporation0078-095800078-0958-19

Other NDCs under BLA 125646

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under BLA 125646
ProductStrengthForm · routeLabelerProduct NDC
KymriahtisagenlecleucelTisagenlecleucel 60000000 1/1Injection, SuspensionIntravenousNovartis Pharmaceuticals Corporation0078-0958

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