Arthrotec NDC 0025-1411

NDC codes

FDA NDC Directory

Product NDC (as listed)0025-1411Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00025-1411Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
0025-1411-60	00025141160	60 TABLET, FILM COATED in 1 BOTTLE (0025-1411-60)Marketed from Dec 24, 1997
0025-1411-90	00025141190	90 TABLET, FILM COATED in 1 BOTTLE (0025-1411-90)Marketed from Dec 24, 1997

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Arthrotec
Generic name (nonproprietary): diclofenac sodium and misoprostol
Active ingredients: Diclofenac sodium — 50 mg/1Misoprostol — 200 ug/1
Dosage form: Tablet, Film coated
Route: Oral
Labeler: Pfizer Laboratories Div Pfizer Inc
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 020607
Marketing start: Dec 24, 1997
Listing expires: Dec 31, 2026
Other FDA classes: Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)Decreased Prostaglandin Production (Physiologic effect)Synthetic (Chemical structure)
Identifiers: Product ID 0025-1411_2b1bf1d7-4399-46bd-8654-2590513da5c2SPL ID 2b1bf1d7-4399-46bd-8654-2590513da5c2SPL set ID 600fe842-45d9-4d68-9ef2-456dbbebaa11RxCUI 857706, 1359105, 1359107, 1359109UNII 0E43V0BB57, QTG126297QUPC 0300251411601, 0300251421600
Pharmacologic class: Nonsteroidal Anti-inflammatory Drug; Prostaglandin E1 Analog

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400025141160 followed by a unit qualifier and the quantity

Package 00025-1411-60. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Aug 14, 2025. This label includes a boxed warning.

Indications (excerpt from the label)

ARTHROTEC is indicated for treatment of the signs and symptoms of osteoarthritis or rheumatoid arthritis in adult patients at high risk of developing NSAID-induced gastric and duodenal ulcers and their complications. For a list of factors that may increase the risk of NSAID-induced gastric and duodenal ulcers and their complications [see Warnings and Precautions (5.3) ] . ARTHROTEC is a combination of diclofenac sodium, a non-steroidal anti-inflammatory drug, and misoprostol, a prostaglandin-1 (PGE1) analog, indicated for the treatment of signs and symptoms of osteoarthritis or rheumatoid arthritis in adult patients at high risk of developing NSAID-induced gastric and duodenal ulcers and the…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 020607

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 020607
Product	Strength	Form · route	Labeler	Product NDC
Arthrotecdiclofenac sodium and misoprostol	Diclofenac sodium 75 mg/1; Misoprostol 200 ug/1	Tablet, Film coatedOral	Pfizer Laboratories Div Pfizer Inc	0025-1421
Diclofenac sodium and Misoprostol DRdiclofenac sodium and misoprostol	Diclofenac sodium 75 mg/1; Misoprostol 200 ug/1	Tablet, Film coatedOral	Advanced Rx Pharmacy of Tennessee, LLC	80425-0272
Diclofenac sodium and Misoprostol	Diclofenac sodium 50 mg/1; Misoprostol 200 ug/1	Tablet, Film coatedOral	Mylan Pharmaceuticals Inc.	59762-0028
Diclofenac sodium and Misoprostol	Diclofenac sodium 75 mg/1; Misoprostol 200 ug/1	Tablet, Film coatedOral	Mylan Pharmaceuticals Inc.	59762-0029