Combigan NDC 0023-9211

NDC codes

FDA NDC Directory

Product NDC (as listed)0023-9211Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00023-9211Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
0023-9211-03	00023921103	1 BOTTLE, DROPPER in 1 CARTON (0023-9211-03) / 2.5 mL in 1 BOTTLE, DROPPERMarketed from Nov 14, 2007 · Sample package
0023-9211-05	00023921105	1 BOTTLE, DROPPER in 1 CARTON (0023-9211-05) / 5 mL in 1 BOTTLE, DROPPERMarketed from Nov 14, 2007
0023-9211-10	00023921110	1 BOTTLE, DROPPER in 1 CARTON (0023-9211-10) / 10 mL in 1 BOTTLE, DROPPERMarketed from Nov 14, 2007
0023-9211-15	00023921115	1 BOTTLE, DROPPER in 1 CARTON (0023-9211-15) / 15 mL in 1 BOTTLE, DROPPERMarketed from Nov 14, 2007

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Combigan
Generic name (nonproprietary): brimonidine tartrate, timolol maleate
Active ingredients: Brimonidine tartrate — 2 mg/mLTimolol maleate — 5 mg/mL
Dosage form: Solution/ drops
Route: Ophthalmic
Labeler: Allergan, Inc.
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 021398
Marketing start: Nov 14, 2007
Listing expires: Dec 31, 2027
Other FDA classes: Adrenergic alpha-Agonists (Mechanism)Adrenergic beta-Antagonists (Mechanism)
Identifiers: Product ID 0023-9211_fa68af94-117a-436f-a3ea-cd0edde443d4SPL ID fa68af94-117a-436f-a3ea-cd0edde443d4SPL set ID feaf1480-a4b8-4486-992a-96be3a596243RxCUI 861635, 861637UNII 4S9CL2DY2H, P8Y54F701R
Pharmacologic class: alpha-Adrenergic Agonist; beta-Adrenergic Blocker

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Ophthalmic products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400023921103 followed by a unit qualifier and the quantity

Package 00023-9211-03. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 17, 2026.

Indications (excerpt from the label)

COMBIGAN ® is indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP. The IOP-lowering of COMBIGAN dosed twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol maleate ophthalmic solution dosed twice a day and 0.2% brimonidine tartrate ophthalmic solution dosed three times per day. COMBIGAN is a combination of brimonidine tartrate, an alpha-adrenergic receptor agonist, and timolol maleate, a beta-adrenergic receptor inhibitor, indicated for the reduction of elevated intraocular pressure (IOP) in patients with g…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)