What is NDC 0023-2181?

0023-2181 is the product NDC for Acular (ketorolac tromethamine), Ketorolac tromethamine 5 mg/mL solution/ drops, listed with the FDA by Allergan, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Acular (Ketorolac Tromethamine).

Allergan, Inc., NDC labeler code 0023. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Acular?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Acular NDC 0023-2181 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)0023-2181Labeler and product segments. Claims need a package NDC.

Product NDC at billing width00023-2181Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
0023-2181-05	00023218105	1 BOTTLE, DROPPER in 1 CARTON (0023-2181-05) / 5 mL in 1 BOTTLE, DROPPERMarketed from Dec 1, 1992

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Acular
Generic name (nonproprietary): ketorolac tromethamine
Active ingredients: Ketorolac tromethamine — 5 mg/mL
Dosage form: Solution/ drops
Route: Ophthalmic
Labeler: Allergan, Inc.NDC labeler code 0023
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 019700
Marketing start: Dec 1, 1992
Listing expires: Dec 31, 2026
Other FDA classes: Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)
Identifiers: Product ID 0023-2181_fb99e487-9880-4bb9-9271-7bf042a4f0f8SPL ID fb99e487-9880-4bb9-9271-7bf042a4f0f8SPL set ID c94644d3-7b64-4f3d-a0c7-12c77466a0fcRxCUI 860107, 860109UNII 4EVE5946BQ
Pharmacologic class: Cyclooxygenase Inhibitor; Nonsteroidal Anti-inflammatory Drug

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Ophthalmic products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400023218105 followed by a unit qualifier and the quantity

Package 00023-2181-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Sep 18, 2025.

Indications (excerpt from the label)

ACULAR is indicated for the temporary relief of ocular itching due to seasonal allergic conjunctivitis. ACULAR is also indicated for the treatment of postoperative inflammation in patients who have undergone cataract extraction. ACULAR is a nonsteroidal anti-inflammatory drug (NSAID) indicated for: The temporary relief of ocular itching due to seasonal allergic conjunctivitis. ( 1 ) The treatment of inflammation following cataract surgery. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 0023-2181

What is NDC 0023-2181?: 0023-2181 is the product NDC for Acular (ketorolac tromethamine), Ketorolac tromethamine 5 mg/mL solution/ drops, listed with the FDA by Allergan, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Acular (Ketorolac Tromethamine).
What is the active ingredient?: Ketorolac tromethamine.
Who is the labeler?: Allergan, Inc., NDC labeler code 0023. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Acular?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Acular (Ketorolac tromethamine) NDC 0023-2181