No. J2506 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J2506?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 3 NDCs under J2506, for Neulasta. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J2506?

$201.241 per 0.5 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

What is one billing unit of J2506?

One unit of J2506 is 0.5 mg, as stated in the code's descriptor. Units to report = dose given ÷ 0.5 mg.

J2506 J-Code: Neulasta (pegfilgrastim) — Billing Units

In short

J2506 is the HCPCS Level II code for injection, pegfilgrastim, excludes biosimilar, 0.5 mg. CMS assigns NDCs for Neulasta to it. One billing unit is 0.5 mg. The Medicare Part B payment limit is $201.241 per unit (October 1, 2026 through December 31, 2026).

Code

Med-Code curated

HCPCS codeJ2506

Billing unit0.5 mg

Descriptor: Injection, pegfilgrastim, excludes biosimilar, 0.5 mg
Code set: HCPCS Level II, maintained by CMS
Category: Colony Stimulating Factor

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$201.241

Per0.5 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 0.5 mg. For example, 50 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 0.5 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Drugs mapped to J2506

FDA-listed products billed under J2506

Finished products in the FDA NDC Directory whose brand or single active ingredient, and route, match this code’s entry.

NDC products matching J2506
Product	Strength	Form · route	Labeler	Product NDC
Armlupegpegfilgrastim-unne	Pegfilgrastim 6 mg/.6mL	InjectionSubcutaneous	Lupin Pharmaceuticals, Inc.	70748-273
Fulphilapegfilgrastim-jmdb	Pegfilgrastim 6 mg/.6mL	InjectionSubcutaneous	Biocon Biologics Inc.	83257-005
Fylnetrapegfilgrastim	Pegfilgrastim 6 mg/.6mL	InjectionSubcutaneous	Amneal Pharmaceuticals LLC	70121-1627
Neulastapegfilgrastim	Pegfilgrastim 4 mg/.4mL	SolutionSubcutaneous	Amgen, Inc	55513-099
Neulastapegfilgrastim	Pegfilgrastim 6 mg/.6mL	InjectionSubcutaneous	Amgen, Inc	55513-190
Nyvepriapegfilgrastim-apgf	Pegfilgrastim 6 mg/.6mL	Injection, SolutionSubcutaneous	Pfizer Laboratories Div Pfizer Inc	0069-0324
Udenycapegfilgrastim-cbqv	Pegfilgrastim 6 mg/.6mL	Injection, SolutionSubcutaneous	Accord BioPharma, Inc.	69448-025
Udenycapegfilgrastim-cbqv	Pegfilgrastim 6 mg/.6mL	Injection, SolutionSubcutaneous	Accord BioPharma, Inc.	69448-026
Udenycapegfilgrastim-cbqv	Pegfilgrastim 6 mg/.6mL	Injection, SolutionSubcutaneous	Accord BioPharma, Inc.	69448-027
Udenycapegfilgrastim-cbqv	Pegfilgrastim 6 mg/.6mL	Injection, SolutionSubcutaneous	Coherus Oncology, Inc.	70114-101
Udenycapegfilgrastim-cbqv	Pegfilgrastim 6 mg/.6mL	Injection, SolutionSubcutaneous	Coherus Oncology, Inc.	70114-120
Udenycapegfilgrastim-cbqv	Pegfilgrastim 6 mg/.6mL	Injection, SolutionSubcutaneous	Coherus Oncology, Inc.	70114-130
Ziextenzopegfilgrastim-bmez	Pegfilgrastim 6 mg/.6mL	InjectionSubcutaneous	Sandoz Inc	61314-866

All NDCs for these drugs

NDCs billed under J2506

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 3 NDCs to J2506 for Neulasta. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J2506 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Neulasta	55513-0099-01	Amgen Inc	0.4	8
Neulasta	55513-0190-01	Amgen Inc	0.6	12
Neulasta	55513-0192-01	Amgen Inc	0.6	12

J2506: common questions

Is J2506 a CPT code?: No. J2506 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J2506?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 3 NDCs under J2506, for Neulasta. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J2506?: $201.241 per 0.5 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J2506?: One unit of J2506 is 0.5 mg, as stated in the code's descriptor. Units to report = dose given ÷ 0.5 mg. J-code billing units.

J2506 — Injection, pegfilgrastim, excludes biosimilar, 0.5 mg