HCPCS drug code · CMS crosswalk
Piperacillin Sodium-Tazobactam Sodium J-Code / HCPCS Code
In short
Piperacillin Sodium-Tazobactam Sodium is billed under HCPCS J2543 — Injection, piperacillin sodium/tazobactam sodium, 1 gram/0.125 grams (1.125 grams). One billing unit is 1.125 gm. CMS's crosswalk lists 71 Piperacillin Sodium-Tazobactam Sodium NDCs under this code.
Reference
- J2543
- Injection, piperacillin sodium/tazobactam sodium, 1 gram/0.125 grams (1.125 grams)Billing unit: 1.125 gm
- Labelers
- Apollo Pharmaceuticals; Apollo Pharmaceuticals Inc.; Apotex Corp; Armas Pharmaceuticals Inc.; Athenex Pharmaceutical Division, LLC; Avenacy Inc.; B. Braun Medical Inc.; BluePoint Laboratoriesand 8 more
Medicare Part B payment limit
CMS ASP filePayment limit per unit$1.183
Per1.125 gm
Coinsurance20%
Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Piperacillin Sodium-Tazobactam Sodium units and claim line
Enter the dose given to get the J2543 units and the NDC line for the CMS-1500 and the 837P.
Enter the units to build the claim line.
Piperacillin Sodium-Tazobactam Sodium NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00264-3446-11 | J2543 | B. Braun Medical Inc. | 24 × 1 | 48 |
| 00264-3448-11 | J2543 | B. Braun Medical Inc. | 24 × 1 | 72 |
| 00264-3450-22 | J2543 | B. Braun Medical Inc. | 24 × 1 | 96 |
| 00409-2999-14 | J2543 | Pfizer Inc | 1 | 12 |
| 00409-3374-02 | J2543 | Pfizer Inc | 10 × 1 | 20 |
| 00409-3378-13 | J2543 | Pfizer Inc | 10 × 1 | 30 |
| 00409-3379-04 | J2543 | Pfizer Inc | 10 × 1 | 40 |
| 00409-3383-02 | J2543 | Pfizer Inc | 10 × 1 | 20 |
| 00409-3383-10 | J2543 | Pfizer Inc | 10 × 1 | 20 |
| 00409-3385-13 | J2543 | Pfizer Inc | 10 × 1 | 30 |
| 00409-3385-15 | J2543 | Pfizer Inc | 10 × 1 | 30 |
| 00409-3390-04 | J2543 | Pfizer Inc | 10 × 1 | 40 |
| 00781-3110-95 | J2543 | Sandoz Inc. | 10 × 1 | 20 |
| 00781-3113-95 | J2543 | Sandoz Inc. | 10 × 1 | 30 |
| 00781-3114-95 | J2543 | Sandoz Inc. | 10 × 1 | 40 |
| 00781-3180-94 | J2543 | Sandoz Inc. | 1 | 36 |
| 00781-9210-95 | J2543 | Sandoz Inc. | 10 × 1 | 20 |
| 00781-9213-95 | J2543 | Sandoz Inc. | 10 × 1 | 30 |
| 00781-9214-95 | J2543 | Sandoz Inc. | 10 × 1 | 40 |
| 25021-0164-30 | J2543 | Sagent Pharmaceuticals | 10 × 1 | 20 |
| 25021-0165-30 | J2543 | Sagent Pharmaceuticals | 10 × 1 | 30 |
| 25021-0166-48 | J2543 | Sagent Pharmaceuticals | 10 × 1 | 40 |
| 25021-0181-99 | J2543 | Sagent Pharmaceuticals | 1 | 36 |
| 44567-0801-10 | J2543 | WG Critical Care, LLC | 10 × 1 | 20 |
| 44567-0802-10 | J2543 | WG Critical Care, LLC | 10 × 1 | 30 |
| 44567-0803-10 | J2543 | WG Critical Care, LLC | 10 × 1 | 40 |
| 44567-0804-01 | J2543 | WG Critical Care, LLC | 1 | 36 |
| 55150-0119-30 | J2543 | Eugia US LLC | 10 × 1 | 20 |
| 55150-0120-30 | J2543 | Eugia US LLC | 10 × 1 | 30 |
| 55150-0121-50 | J2543 | Eugia US LLC | 10 × 1 | 40 |
| 60505-6156-04 | J2543 | Apotex Corp | 10 × 1 | 20 |
| 60505-6157-04 | J2543 | Apotex Corp | 10 × 1 | 30 |
| 60505-6159-04 | J2543 | Apotex Corp | 10 × 1 | 40 |
| 60505-6262-00 | J2543 | Apotex Corp | 1 | 36 |
| 61990-0110-02 | J2543 | Apollo Pharmaceuticals Inc. | 10 × 1 | 20 |
| 61990-0120-02 | J2543 | Apollo Pharmaceuticals Inc. | 10 × 1 | 30 |
| 61990-0130-02 | J2543 | Apollo Pharmaceuticals Inc. | 10 × 1 | 40 |
| 61990-0150-01 | J2543 | Apollo Pharmaceuticals Inc. | 1 | 36 |
| 63323-0981-21 | J2543 | FreseniUS Kabi USA, LLC | 10 × 1 | 20 |
| 63323-0981-53 | J2543 | FreseniUS Kabi USA, LLC | 10 × 1 | 20 |
| 63323-0983-21 | J2543 | FreseniUS Kabi USA, LLC | 10 × 1 | 30 |
| 63323-0983-53 | J2543 | FreseniUS Kabi USA, LLC | 10 × 1 | 30 |
| 65219-0256-00 | J2543 | FreseniUS Kabi USA, LLC | 1 | 36 |
| 65219-0256-24 | J2543 | FreseniUS Kabi USA, LLC | 1 | 36 |
| 65219-0256-28 | J2543 | FreseniUS Kabi USA, LLC | 1 | 36 |
| 65219-0259-45 | J2543 | FreseniUS Kabi USA, LLC | 10 × 1 | 40 |
| 65219-0259-55 | J2543 | FreseniUS Kabi USA, LLC | 10 × 1 | 40 |
| 65219-0434-20 | J2543 | FreseniUS Kabi USA, LLC | 10 × 1 | 20 |
| 65219-0436-20 | J2543 | FreseniUS Kabi USA, LLC | 10 × 1 | 30 |
| 66794-0216-41 | J2543 | Piramal Critical Care Inc | 10 × 1 | 20 |
| 66794-0217-41 | J2543 | Piramal Critical Care Inc | 10 × 1 | 30 |
| 66794-0218-41 | J2543 | Piramal Critical Care Inc | 10 × 1 | 40 |
| 68001-0506-30 | J2543 | BluePoint Laboratories | 10 × 1 | 20 |
| 68001-0507-82 | J2543 | BluePoint Laboratories | 10 × 1 | 30 |
| 68001-0508-31 | J2543 | BluePoint Laboratories | 10 × 1 | 40 |
| 70860-0120-20 | J2543 | Athenex Pharmaceutical Division, LLC | 10 × 1 | 20 |
| 70860-0121-30 | J2543 | Athenex Pharmaceutical Division, LLC | 10 × 1 | 30 |
| 70860-0122-50 | J2543 | Athenex Pharmaceutical Division, LLC | 10 × 1 | 40 |
| 70860-0123-99 | J2543 | Athenex Pharmaceutical Division, LLC | 1 | 36 |
| 72485-0403-10 | J2543 | Armas Pharmaceuticals Inc. | 10 × 1 | 30 |
| 72485-0404-10 | J2543 | Armas Pharmaceuticals Inc. | 10 × 1 | 40 |
| 72572-0414-10 | J2543 | Civica, Inc. | 10 × 1 | 30 |
| 72572-0418-10 | J2543 | Civica, Inc. | 10 × 1 | 40 |
| 72572-0573-10 | J2543 | Civica, Inc. | 10 × 1 | 30 |
| 72572-0574-10 | J2543 | Civica, Inc. | 10 × 1 | 40 |
| 81284-0151-10 | J2543 | Apollo Pharmaceuticals | 10 × 1 | 20 |
| 81284-0152-10 | J2543 | Apollo Pharmaceuticals | 10 × 1 | 30 |
| 81284-0154-01 | J2543 | Apollo Pharmaceuticals | 1 | 12 |
| 81284-0155-01 | J2543 | Apollo Pharmaceuticals | 1 | 36 |
| 83634-0106-50 | J2543 | Avenacy Inc. | 10 × 1 | 40 |
| 81284-0153-10 | J2543 | Apollo Pharmaceuticals | 10 × 1 | 40 |
Piperacillin Sodium-Tazobactam Sodium: common questions
- What is the J-code for Piperacillin Sodium-Tazobactam Sodium?
- Piperacillin Sodium-Tazobactam Sodium is billed under HCPCS J2543 — Injection, piperacillin sodium/tazobactam sodium, 1 gram/0.125 grams (1.125 grams). One billing unit is 1.125 gm. CMS's crosswalk lists 71 Piperacillin Sodium-Tazobactam Sodium NDCs under this code.
- How many J2543 billing units are in a package of Piperacillin Sodium-Tazobactam Sodium?
- CMS lists 12 to 96 billing units per package, depending on the NDC, where one unit is 1.125 gm. Units to report are based on the dose given, not the package.
- Is J2543 a CPT code?
- No. J2543 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.