How many Q5112 billing units are in a package of Ontruzant?

CMS lists 15 to 42 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.

No. Q5112 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Ontruzant HCPCS Code Q5112 — Billing Units & NDCs

In short

Ontruzant is billed under HCPCS Q5112 — Injection, trastuzumab-dttb, biosimilar, (ontruzant), 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Ontruzant NDCs under this code.

Q5112 code details

Reference

Q5112: Injection, trastuzumab-dttb, biosimilar, (ontruzant), 10 mgBilling unit: 10 mg
Labelers: Organon LLC

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$32.791

Per10 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: 8% of reference add-on applied. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Ontruzant units and claim line

Enter the dose given to get the Q5112 units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 10 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Ontruzant NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Ontruzant NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
78206-0147-01	Q5112	Organon LLC	150	15
78206-0148-01	Q5112	Organon LLC	420	42

Ontruzant: common questions

What is the HCPCS code for Ontruzant?: Ontruzant is billed under HCPCS Q5112 — Injection, trastuzumab-dttb, biosimilar, (ontruzant), 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Ontruzant NDCs under this code.
How many Q5112 billing units are in a package of Ontruzant?: CMS lists 15 to 42 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is Q5112 a CPT code?: No. Q5112 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Ontruzant HCPCS Code

Reference

Medicare Part B payment limit

Ontruzant units and claim line

Ontruzant NDCs and billing units

Ontruzant: common questions

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Reference

Medicare Part B payment limit

Ontruzant units and claim line

Ontruzant NDCs and billing units

Ontruzant: common questions

Other codes for the same drug

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