In short

Marcaine is billed under HCPCS J0665 — Injection, bupivicaine, not otherwise specified, 0.5 mg. One billing unit is 0.5 mg. CMS's crosswalk lists 19 Marcaine NDCs under this code.

J0665 code details

Reference

J0665
Injection, bupivicaine, not otherwise specified, 0.5 mgBilling unit: 0.5 mg
Labelers
Henry Schein Inc.; Pfizer Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.01
Per0.5 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Marcaine units and claim line

Enter the dose given to get the J0665 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Marcaine NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Marcaine NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00404-9768-30J0665Henry Schein Inc.30300
00404-9770-10J0665Henry Schein Inc.1050
00404-9906-10J0665Henry Schein Inc.1050
00404-9907-10J0665Henry Schein Inc.10100
00404-9907-30J0665Henry Schein Inc.30300
00409-0525-25J0665Pfizer Inc25 × 5012500
00409-1530-25J0665Pfizer Inc25 × 307500
00409-1559-10J0665Pfizer Inc10 × 10500
00409-1559-30J0665Pfizer Inc10 × 301500
00409-1560-10J0665Pfizer Inc10 × 101000
00409-1560-29J0665Pfizer Inc10 × 303000
00409-1582-10J0665Pfizer Inc10 × 101500
00409-1582-29J0665Pfizer Inc10 × 304500
00409-1587-50J0665Pfizer Inc50250
00409-1610-50J0665Pfizer Inc50500
00409-2253-25J0665Pfizer Inc25 × 3011250
00409-2510-25J0665Pfizer Inc25 × 101250
00409-5010-25J0665Pfizer Inc25 × 102500
00409-7535-25J0665Pfizer Inc25 × 303750

Marcaine: common questions

What is the J-code for Marcaine?
Marcaine is billed under HCPCS J0665 — Injection, bupivicaine, not otherwise specified, 0.5 mg. One billing unit is 0.5 mg. CMS's crosswalk lists 19 Marcaine NDCs under this code.
How many J0665 billing units are in a package of Marcaine?
CMS lists 50 to 12,500 billing units per package, depending on the NDC, where one unit is 0.5 mg. Units to report are based on the dose given, not the package.
Is J0665 a CPT code?
No. J0665 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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